Extensive Variation in Gene Copy Number at the Killer Immunoglobulin-Like Receptor Locus in Humans

Extensive Variation in Gene Copy Number at the Killer Immunoglobulin-Like Receptor Locus in Humans

Killer immunoglobulin-like receptors (KIRs) are involved in the regulation of natural killer cell cytotoxicity. Within the human genome seventeen KIR genes are present, which all contain a large number of allelic variants. The high level of homology among KIR genes has hampered KIR genotyping in lar...

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Bibliographic Details
Main Authors: Vendelbosch, Sanne, de Boer, Martin, Gouw, Remko A. T. W., Ho, Cynthia K. Y., Geissler, Judy, Swelsen, Wendy T. N., Moorhouse, Michael J., Lardy, Neubury M., Roos, Dirk, van den Berg, Timo K., Kuijpers, Taco W.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695908/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695908/

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