Complement Factor H-Related Protein 3 Serum Levels Are Low Compared to Factor H and Mainly Determined by Gene Copy Number Variation in CFHR3

Complement Factor H-Related Protein 3 Serum Levels Are Low Compared to Factor H and Mainly Determined by Gene Copy Number Variation in CFHR3

The major human complement regulator in blood, complement factor H (FH), has several closely related proteins, called FH-related (FHR) proteins. As all FHRs lack relevant complement regulatory activity, their physiological role is not well understood. FHR protein 3 (FHR-3) has been suggested to comp...

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Bibliographic Details
Main Authors: Pouw, Richard B., Brouwer, Mieke C., Geissler, Judy, van Herpen, Laurens V., Zeerleder, Sacha S., Wuillemin, Walter A., Wouters, Diana, Kuijpers, Taco W.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805260/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805260/

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