Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis

► High dietary vitamin D was able to prevent premalignant lesions caused by AOM/DSS. ► Increasing vitamin D intake raised serum 25-D3 levels reaching a plateau ≥1000 IU/kg. ► Serum 25-D3 levels over 30 ng/ml are needed to prevent tumorigenesis.

Bibliographic Details
Main Authors: Hummel, Doris Maria, Thiem, Ursula, Höbaus, Julia, Mesteri, Ildiko, Gober, Lukas, Stremnitzer, Caroline, Graça, João, Obermayer-Pietsch, Barbara, Kallay, Enikö
Format: Online
Language:English
Published: Pergamon 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695567/
id pubmed-3695567
recordtype oai_dc
spelling pubmed-36955672013-07-01 Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis Hummel, Doris Maria Thiem, Ursula Höbaus, Julia Mesteri, Ildiko Gober, Lukas Stremnitzer, Caroline Graça, João Obermayer-Pietsch, Barbara Kallay, Enikö Article ► High dietary vitamin D was able to prevent premalignant lesions caused by AOM/DSS. ► Increasing vitamin D intake raised serum 25-D3 levels reaching a plateau ≥1000 IU/kg. ► Serum 25-D3 levels over 30 ng/ml are needed to prevent tumorigenesis. Pergamon 2013-07 /pmc/articles/PMC3695567/ /pubmed/22982628 http://dx.doi.org/10.1016/j.jsbmb.2012.09.003 Text en © 2013 Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/3.0/ Open Access under CC BY-NC-ND 3.0 (https://creativecommons.org/licenses/by-nc-nd/3.0/) license
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Hummel, Doris Maria
Thiem, Ursula
Höbaus, Julia
Mesteri, Ildiko
Gober, Lukas
Stremnitzer, Caroline
Graça, João
Obermayer-Pietsch, Barbara
Kallay, Enikö
spellingShingle Hummel, Doris Maria
Thiem, Ursula
Höbaus, Julia
Mesteri, Ildiko
Gober, Lukas
Stremnitzer, Caroline
Graça, João
Obermayer-Pietsch, Barbara
Kallay, Enikö
Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis
author_facet Hummel, Doris Maria
Thiem, Ursula
Höbaus, Julia
Mesteri, Ildiko
Gober, Lukas
Stremnitzer, Caroline
Graça, João
Obermayer-Pietsch, Barbara
Kallay, Enikö
author_sort Hummel, Doris Maria
title Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis
title_short Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis
title_full Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis
title_fullStr Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis
title_full_unstemmed Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis
title_sort prevention of preneoplastic lesions by dietary vitamin d in a mouse model of colorectal carcinogenesis
description ► High dietary vitamin D was able to prevent premalignant lesions caused by AOM/DSS. ► Increasing vitamin D intake raised serum 25-D3 levels reaching a plateau ≥1000 IU/kg. ► Serum 25-D3 levels over 30 ng/ml are needed to prevent tumorigenesis.
publisher Pergamon
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695567/
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