Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis

► High dietary vitamin D was able to prevent premalignant lesions caused by AOM/DSS. ► Increasing vitamin D intake raised serum 25-D3 levels reaching a plateau ≥1000 IU/kg. ► Serum 25-D3 levels over 30 ng/ml are needed to prevent tumorigenesis.

Bibliographic Details
Main Authors: Hummel, Doris Maria, Thiem, Ursula, Höbaus, Julia, Mesteri, Ildiko, Gober, Lukas, Stremnitzer, Caroline, Graça, João, Obermayer-Pietsch, Barbara, Kallay, Enikö
Format: Online
Language:English
Published: Pergamon 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695567/