Transforming growth factor-β1 selectively inhibits hepatocyte growth factor expression via a micro-RNA-199–dependent posttranscriptional mechanism
Hepatocyte growth factor (HGF) is a multipotent endogenous repair factor. The profibrotic cytokine transforming growth factor (TGF)-β1 inhibits HGF expression by a micro-RNA-199 (miR-199)-dependent posttranscriptional mechanism. In contrast, NK2, a truncated isoform of HGF that inhibits normal repai...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694793/ |