Transforming growth factor-β and breast cancer: Transforming growth factor-β/SMAD signaling defects and cancer
Transforming growth factor-β (TGF-β) is a tumor suppressor, the function of which is compromised in many types of human cancer, including breast cancer. The tumor suppressive effects of TGF-β are caused by potent inhibition of cell proliferation due to cell cycle arrest in the G1 phase. Such antipro...
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| Format: | Online |
| Language: | English |
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BioMed Central
2000
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139432/ |