A Human/Murine Chimeric Fab Antibody Neutralizes Anthrax Lethal Toxin In Vitro

Human anthrax infection caused by exposure to Bacillus anthracis cannot always be treated by antibiotics. This is mostly because of the effect of the remaining anthrax toxin in the body. Lethal factor (LF) is a component of lethal toxin (LeTx), which is the major virulence of anthrax toxin. A murine...

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Bibliographic Details
Main Authors: Ding, Guipeng, Chen, Ximin, Zhu, Jin, Duesbery, Nicholas S., Cheng, Xunjia, Cao, Brian
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687597/