Development of an in Vitro Potency Assay for Anti-anthrax Lethal Toxin Neutralizing Antibodies

Lethal toxin (LT) of Bacillus anthracis reduces the production of a number of inflammatory mediators, including transcription factors, chemokines and cytokines in various human cell lines, leading to down-regulation of the host inflammatory response. Previously we showed that the reduction of interl...

Full description

Bibliographic Details
Main Authors: Whiting, Gail, Baker, Michael, Rijpkema, Sjoerd
Format: Online
Language:English
Published: MDPI 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277096/