Genetic variation in PARL influences mitochondrial content

Given their involvement in processes necessary for life, mitochondrial damage and subsequent dysfunction can lead to a wide range of human diseases. Previous studies of both animal models and humans have suggested that presenilins-associated rhomboid-like protein (PARL) is a key regulator of mitocho...

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Bibliographic Details
Main Authors: Curran, J., Jowett, J., Abraham, L., Diepeveen, L., Elliott, K., Dyer, T., Kerr-Bayles, L., Johnson, M., Comuzzie, A., Moses, Eric, Walder, K., Collier, G., Blangero, J., Kissebah, A.
Format: Journal Article
Published: 2010
Online Access:http://hdl.handle.net/20.500.11937/7519