Inhibition of apelin expression switches endothelial cells from proliferative to mature state in pathological retinal angiogenesis

The recruitment of mural cells such as pericytes to patent vessels with an endothelial lumen is a key factor for the maturation of blood vessels and the prevention of hemorrhage in pathological angiogenesis. To date, our understanding of the specific trigger underlying the transition from cell growt...

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Bibliographic Details
Main Authors: Kasai, Atsushi, Ishimaru, Yuki, Higashino, Kosuke, Kobayashi, Kohei, Yamamuro, Akiko, Yoshioka, Yasuhiro, Maeda, Sadaaki
Format: Online
Language:English
Published: Springer Netherlands 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682100/