Apelin Deficiency Accelerates the Progression of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the selective loss of motor neurons. Recent studies have implicated that chronic hypoxia and insufficient vascular endothelial growth factor (VEGF)-dependent neuroprotection may lead to the degeneration of motor neur...

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Bibliographic Details
Main Authors: Kasai, Atsushi, Kinjo, Toshihiko, Ishihara, Rie, Sakai, Ikumi, Ishimaru, Yuki, Yoshioka, Yasuhiro, Yamamuro, Akiko, Ishige, Kumiko, Ito, Yoshihisa, Maeda, Sadaaki
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161091/