Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9

by Shen, Bang, Brown, Kevin M., Lee, Tobie D., Sibley, L. David
Published 2014

The Volatile Anesthetic Isoflurane Increases Endothelial Adenosine Generation via Microparticle Ecto-5′-Nucleotidase (CD73) Release

by Kim, Mihwa, Ham, Ahrom, Kim, Katelyn Yu-Mi, Brown, Kevin M., Lee, H. Thomas
Published 2014

Inter-Platform comparability of microarrays in acute lymphoblastic leukemia

by Mitchell, Stephanie A, Brown, Kevin M, Henry, Michael M, Mintz, Michelle, Catchpoole, Daniel, LaFleur, Bonnie, Stephan, Dietrich A
Published 2004

The volatile anesthetic isoflurane induces ecto-5′-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury

by Kim, Mihwa, Ham, Ahrom, Kim, Joo Yun, Brown, Kevin M., D’Agati, Vivette D., Lee, H. Thomas
Published 2013

Selective deletion of the endothelial sphingosine-1-phosphate 1 receptor exacerbates kidney ischemia-reperfusion injury

by Ham, Ahrom, Kim, Mihwa, Kim, Joo Yun, Brown, Kevin M., Fruttiger, Marcus, D’Agati, Vivette D., Lee, H. Thomas
Published 2013

Whole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondii

by Farrell, Andrew, Coleman, Bradley I, Benenati, Brian, Brown, Kevin M, Blader, Ira J, Marth, Gabor T, Gubbels, Marc-Jan
Published 2014

Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk

by Law, Matthew H., Montgomery, Grant W., Brown, Kevin M., Martin, Nicholas G., Mann, Graham J., Hayward, Nicholas K., MacGregor, Stuart
Published 2011

Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia

by Park, Sang Won, Kim, Mihwa, Kim, Joo Yun, Brown, Kevin M., Haase, Volker H., D’Agati, Vivette D., Lee, H. Thomas
Published 2012

A BAP1 Mutation in a Danish Family Predisposes to Uveal Melanoma and Other Cancers

by Aoude, Lauren G., Wadt, Karin, Bojesen, Anders, Crüger, Dorthe, Borg, Åke, Trent, Jeffrey M., Brown, Kevin M., Gerdes, Anne-Marie, Jönsson, Göran, Hayward, Nicholas K.
Published 2013

Forward Genetic Screening Identifies a Small Molecule That Blocks Toxoplasma gondii Growth by Inhibiting Both Host- and Parasite-Encoded Kinases

by Brown, Kevin M., Suvorova, Elena, Farrell, Andrew, McLain, Aaron, Dittmar, Ashley, Wiley, Graham B., Marth, Gabor, Gaffney, Patrick M., Gubbels, Marc Jan, White, Michael, Blader, Ira J.
Published 2014

Array-Comparative Genomic Hybridization Reveals Loss of SOCS6 Is Associated with Poor Prognosis in Primary Lung Squamous Cell Carcinoma

by Sriram, Krishna B., Larsen, Jill E., Savarimuthu Francis, Santiyagu M., Wright, Casey M., Clarke, Belinda E., Duhig, Edwina E., Brown, Kevin M., Hayward, Nicholas K., Yang, Ian A., Bowman, Rayleen V., Fong, Kwun M.
Published 2012

Assessment of PALB2 as a Candidate Melanoma Susceptibility Gene

by Aoude, Lauren G., Xu, Mai, Zhao, Zhen Zhen, Kovacs, Michael, Palmer, Jane M., Johansson, Peter, Symmons, Judith, Trent, Jeffrey M., Martin, Nicholas G., Montgomery, Grant W., Brown, Kevin M., Hayward, Nicholas K.
Published 2014

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation

by Kim, Hyungsoo, Frederick, Dennie T., Levesque, Mitchell P., Cooper, Zachary A., Feng, Yongmei, Krepler, Clemens, Brill, Laurence, Samuels, Yardena, Hayward, Nicholas K., Perlina, Ally, Piris, Adriano, Zhang, Tongwu, Halaban, Ruth, Herlyn, Meenhard M., Brown, Kevin M., Wargo, Jennifer A., Dummer, Reinhard, Flaherty, Keith T., Ronai, Ze’ev A.
Published 2015

Germline TERT promoter mutations are rare in familial melanoma

by Harland, Mark, Petljak, Mia, Robles-Espinoza, Carla Daniela, Ding, Zhihao, Gruis, Nelleke A., van Doorn, Remco, Pooley, Karen A., Dunning, Alison M., Aoude, Lauren G., Wadt, Karin A. W., Gerdes, Anne-Marie, Brown, Kevin M., Hayward, Nicholas K., Newton-Bishop, Julia A., Adams, David J., Bishop, D. Timothy
Published 2015

Frequent somatic MAP3K5 and MAP3K9 mutations in metastatic melanoma identified by exome sequencing

by Stark, Mitchell S, Woods, Susan L, Gartside, Michael G, Bonazzi, Vanessa F, Dutton-Regester, Ken, Aoude, Lauren G, Chow, Donald, Sereduk, Chris, Niemi, Natalie M, Tang, Nanyun, Ellis, Jonathan J, Reid, Jeffrey, Zismann, Victoria, Tyagi, Sonika, Muzny, Donna, Newsham, Irene, Wu, YuanQing, Palmer, Jane M, Pollak, Thomas, Youngkin, David, Brooks, Bradford R, Lanagan, Catherine, Schmidt, Christopher W, Kobe, Bostjan, MacKeigan, Jeffrey P, Yin, Hongwei, Brown, Kevin M, Gibbs, Richard, Trent, Jeffrey, Hayward, Nicholas K
Published 2011

POT1 loss-of-function variants predispose to familial melanoma

by Robles-Espinoza, Carla Daniela, Harland, Mark, Ramsay, Andrew J., Aoude, Lauren G., Quesada, Víctor, Ding, Zhihao, Pooley, Karen A., Pritchard, Antonia L., Tiffen, Jessamy C., Petljak, Mia, Palmer, Jane M., Symmons, Judith, Johansson, Peter, Stark, Mitchell S., Gartside, Michael G., Snowden, Helen, Montgomery, Grant W., Martin, Nicholas G., Liu, Jimmy Z., Choi, Jiyeon, Makowski, Matthew, Brown, Kevin M., Dunning, Alison M., Keane, Thomas M., López-Otín, Carlos, Gruis, Nelleke A., Hayward, Nicholas K., Bishop, D. Timothy, Newton-Bishop, Julia A., Adams, David J.
Published 2014

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

by MacGregor, Stuart, Montgomery, Grant W., Liu, Jimmy Z., Zhao, Zhen Zhen, Henders, Anjali K., Stark, Mitchell, Schmid, Helen, Holland, Elizabeth A, Duffy, David L., Zhang, Mingfeng, Painter, Jodie N., Nyholt, Dale R, Maskiell, Judith A., Jetann, Jodie, Ferguson, Megan, Cust, Anne E., Jenkins, Mark A., Whiteman, David C., Olsson, Håkan, Puig, Susana, Bianchi-Scarrà, Giovanna, Hansson, Johan, Demenais, Florence, Landi, Maria Teresa, Dȩbniak, Tadeusz, Mackie, Rona, Azizi, Esther, Bressac - de Paillerets, Brigitte, Goldstein, Alisa M., Kanetsky, Peter A., Gruis, Nelleke A., Elder, David E., Bishop, Julia A. Newton, Bishop, D. Timothy, Iles, Mark M., Helsing, Per, Amos, Christopher I., Wei, Qingyi, Wang, Li-E, Lee, Jeffrey E., Qureshi, Abrar A., Kefford, Richard F., Giles, Graham G., Armstrong, Bruce K., Aitken, Joanne F., Han, Jiali, Hopper, John L., Trent, Jeffrey M., Brown, Kevin M., Martin, Nicholas G., Mann, Graham J., Hayward, Nicholas K.
Published 2011

The Effect on Melanoma Risk of Genes Previously Associated With Telomere Length

by Iles, Mark M., Bishop, D. Timothy, Taylor, John C., Hayward, Nicholas K., Brossard, Myriam, Cust, Anne E., Dunning, Alison M., Lee, Jeffrey E., Moses, Eric K., Akslen, Lars A., Andresen, Per A., Avril, Marie-Françoise, Azizi, Esther, Scarrà, Giovanna Bianchi, Brown, Kevin M., Dębniak, Tadeusz, Elder, David E., Friedman, Eitan, Ghiorzo, Paola, Gillanders, Elizabeth M., Goldstein, Alisa M., Gruis, Nelleke A., Hansson, Johan, Harland, Mark, Helsing, Per, Hočevar, Marko, Höiom, Veronica, Ingvar, Christian, Kanetsky, Peter A., Landi, Maria Teresa, Lang, Julie, Lathrop, G. Mark, Lubiński, Jan, Mackie, Rona M., Martin, Nicholas G., Molven, Anders, Montgomery, Grant W., Novaković, Srdjan, Olsson, Håkan, Puig, Susana, Puig-Butille, Joan Anton, Radford-Smith, Graham L., Randerson-Moor, Juliette, van der Stoep, Nienke, van Doorn, Remco, Whiteman, David C., MacGregor, Stuart, Pooley, Karen A., Ward, Sarah V., Mann, Graham J., Amos, Christopher I., Pharoah, Paul D. P., Demenais, Florence, Law, Matthew H., Newton Bishop, Julia A., Barrett, Jennifer H.
Published 2014

Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions

by Barrett, Jennifer H, Taylor, John C, Bright, Chloe, Harland, Mark, Dunning, Alison M, Akslen, Lars A, Andresen, Per A, Avril, Marie-Françoise, Azizi, Esther, Bianchi Scarrà, Giovanna, Brossard, Myriam, Brown, Kevin M, Dębniak, Tadeusz, Elder, David E, Friedman, Eitan, Ghiorzo, Paola, Gillanders, Elizabeth M, Gruis, Nelleke A, Hansson, Johan, Helsing, Per, Hočevar, Marko, Höiom, Veronica, Ingvar, Christian, Landi, Maria Teresa, Lang, Julie, Lathrop, G Mark, Lubiński, Jan, Mackie, Rona M, Molven, Anders, Novaković, Srdjan, Olsson, Håkan, Puig, Susana, Puig-Butille, Joan Anton, van der Stoep, Nienke, van Doorn, Remco, van Workum, Wilbert, Goldstein, Alisa M, Kanetsky, Peter A, Pharoah, Paul D P, Demenais, Florence, Hayward, Nicholas K, Newton Bishop, Julia A, Bishop, D Timothy, Iles, Mark M
Published 2015

Genome-wide association study identifies three new melanoma susceptibility loci

by Barrett, Jennifer H, Iles, Mark M, Harland, Mark, Taylor, John C, Aitken, Joanne F, Andresen, Per Arne, Akslen, Lars A, Armstrong, Bruce K, Avril, Marie-Francoise, Azizi, Esther, Bakker, Bert, Bergman, Wilma, Bianchi-Scarrà, Giovanna, Paillerets, Brigitte Bressac-de, Calista, Donato, Cannon-Albright, Lisa A, Corda, Eve, Cust, Anne E, Dębniak, Tadeusz, Duffy, David, Dunning, Alison, Easton, Douglas F, Friedman, Eitan, Galan, Pilar, Ghiorzo, Paola, Giles, Graham G, Hansson, Johan, Hocevar, Marko, Höiom, Veronica, Hopper, John L, Ingvar, Christian, Janssen, Bart, Jenkins, Mark A, Jönsson, Göran, Kefford, Richard F, Landi, Giorgio, Landi, Maria Teresa, Lang, Julie, Lubiński, Jan, Mackie, Rona, Malvehy, Josep, Martin, Nicholas G, Molven, Anders, Montgomery, Grant W, van Nieuwpoort, Frans A, Novakovic, Srdjan, Olsson, Håkan, Pastorino, Lorenza, Puig, Susana, Puig-Butille, Joan Anton, Randerson-Moor, Juliette, Snowden, Helen, Tuominen, Rainer, Van Belle, Patricia, van der Stoep, Nienke, Whiteman, David C, Zelenika, Diana, Han, Jiali, Fang, Shenying, Lee, Jeffrey E, Wei, Qingyi, Lathrop, G Mark, Gillanders, Elizabeth M, Brown, Kevin M, Goldstein, Alisa M, Kanetsky, Peter A, Mann, Graham J, MacGregor, Stuart, Elder, David E, Amos, Christopher I, Hayward, Nicholas K, Gruis, Nelleke A, Demenais, Florence, Newton Bishop, Julia A, Bishop, D Timothy
Published 2011