Impact of macromolecular crowding on DNA replication
Enzymatic activities in vivo occur in a crowded environment composed of many macromolecules. This environment influences DNA replication by increasing the concentration of the constituents, desolvation, decreasing the degrees of freedom for diffusion and hopping of proteins onto DNA, and enhancing b...
Main Authors: | Akabayov, Barak, Akabayov, Sabine R., Lee, Seung–Joo, Wagner, Gerhard, Richardson, Charles C. |
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Format: | Online |
Language: | English |
Published: |
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666333/ |
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