Computer-Aided Approaches for Targeting HIVgp41
Virus-cell fusion is the primary means by which the human immunodeficiency virus-1 (HIV) delivers its genetic material into the human T-cell host. Fusion is mediated in large part by the viral glycoprotein 41 (gp41) which advances through four distinct conformational states: (i) native, (ii) pre-hai...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
MDPI
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666032/ |