Approaches for Identification of HIV-1 Entry Inhibitors Targeting gp41 Pocket
The hydrophobic pocket in the HIV-1 gp41 N-terminal heptad repeat (NHR) domain plays an important role in viral fusion and entry into the host cell, and serves as an attractive target for development of HIV-1 fusion/entry inhibitors. The peptide anti-HIV drug targeting gp41 NHR, T-20 (generic name:...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
MDPI
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564113/ |