SRSF1 and SRSF9 RNA binding proteins promote Wnt signalling-mediated tumorigenesis by enhancing β-catenin biosynthesis
Wnt/β-catenin signalling is widely implicated in embryogenesis, tissue homeostasis and tumorigenesis. The key event in Wnt signalling activation is β-catenin accumulation, which is controlled by both its production and degradation. However, much more emphasis has been placed on the understanding of...
Main Authors: | Fu, Yu, Huang, Binlu, Shi, Zhen, Han, Jiayu, Wang, Ying, Huangfu, Jieqiong, Wu, Wei |
---|---|
Format: | Online |
Language: | English |
Published: |
WILEY-VCH Verlag
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662316/ |
Similar Items
-
Regulation of Mcl-1 by SRSF1 and SRSF5 in Cancer Cells
by: Gautrey, Hannah L., et al.
Published: (2012) -
Phosphorylation of SRSF1 is modulated by replicational stress
by: Leva, Valentina, et al.
Published: (2012) -
SRSF1 inhibition of HIV-1 gene expression
by: Paz, Sean, et al.
Published: (2015) -
The SRSF1 linker induces semi-conservative ESE binding by cooperating with the RRMs
by: Cho, Suhyung, et al.
Published: (2011) -
Splicing factor SRSF6 promotes hyperplasia of sensitized skin
by: Jensen, Mads A., et al.
Published: (2014)