Splicing factor SRSF6 promotes hyperplasia of sensitized skin

Many biological processes involve gene-expression regulation by alternative splicing. Here, we identify the splicing factor SRSF6 as a regulator of wound healing and tissue homeostasis in skin. We show that SRSF6 is a proto-oncogene that is frequently overexpressed in human skin cancer. Overexpressi...

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Bibliographic Details
Main Authors: Jensen, Mads A., Wilkinson, John E., Krainer, Adrian R.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118672/