Pioglitazone Acutely Reduces Energy Metabolism and Insulin Secretion in Rats

Pioglitazone Acutely Reduces Energy Metabolism and Insulin Secretion in Rats

Our objective was to determine if the insulin-sensitizing drug pioglitazone acutely reduces insulin secretion and causes metabolic deceleration in vivo independently of change in insulin sensitivity. We assessed glucose homeostasis by hyperinsulinemic-euglycemic and hyperglycemic clamp studies and e...

Full description

Bibliographic Details
Main Authors: Lamontagne, Julien, Jalbert-Arsenault, Élise, Pepin, Émilie, Peyot, Marie-Line, Ruderman, Neil B., Nolan, Christopher J., Joly, Erik, Madiraju, S.R. Murthy, Poitout, Vincent, Prentki, Marc
Format: Online
Language:English
Published: American Diabetes Association 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661607/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661607/

Similar Items