Identification of Antithrombin-Modulating Genes. Role of LARGE, a Gene Encoding a Bifunctional Glycosyltransferase, in the Secretion of Proteins?

Identification of Antithrombin-Modulating Genes. Role of LARGE, a Gene Encoding a Bifunctional Glycosyltransferase, in the Secretion of Proteins?

The haemostatic relevance of antithrombin together with the low genetic variability of SERPINC1, and the high heritability of plasma levels encourage the search for modulating genes. We used a hypothesis-free approach to identify these genes, evaluating associations between plasma antithrombin and 3...

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Bibliographic Details
Main Authors: de la Morena-Barrio, María Eugenia, Buil, Alfonso, Antón, Ana Isabel, Martínez-Martínez, Irene, Miñano, Antonia, Gutiérrez-Gallego, Ricardo, Navarro-Fernández, José, Aguila, Sonia, Souto, Juan Carlos, Vicente, Vicente, Soria, José Manuel, Corral, Javier
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660365/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660365/

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