Heparanase Activates Antithrombin through the Binding to Its Heparin Binding Site

Heparanase is an endoglycosidase that participates in morphogenesis, tissue repair, heparan sulphates turnover and immune response processes. It is over-expressed in tumor cells favoring the metastasis as it penetrates the endothelial layer that lines blood vessels and facilitates the metastasis by...

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Bibliographic Details
Main Authors: Bohdan, Nataliya, Espín, Salvador, Águila, Sonia, Teruel-Montoya, Raúl, Vicente, Vicente, Corral, Javier, Martínez-Martínez, Irene
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913942/