Clinical and pharmacologic aspects of blinatumomab in the treatment of B-cell acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) in adults remains a challenging disease to treat, and novel therapies are needed. Precursor-B ALL comprises 80% of cases, and the CD19 antigen is expressed in nearly all precursor-B ALL patients. Bispecific T-cell-engaging antibodies are novel bioengineered protein...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Dove Medical Press
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650887/ |