Genetic Analysis of Primaquine Tolerance in a Patient with Relapsing Vivax Malaria

Patients with Plasmodium vivax malaria are treated with primaquine to prevent relapse infections. We report primaquine failure in a patient with 3 relapses without any possibility of re-infection. Using whole genome sequencing of the relapsing parasite isolates, we identified single nucleotide varia...

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Bibliographic Details
Main Authors: Bright, A. Taylor, Alenazi, Thamer, Shokoples, Sandra, Tarning, Joel, Paganotti, Giacomo M., White, Nicholas J., Houston, Stanley, Winzeler, Elizabeth A., Yanow, Stephanie K.
Format: Online
Language:English
Published: Centers for Disease Control and Prevention 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647516/