Dihydroartemisinin induces autophagy and inhibits the growth of iron-loaded human myeloid leukemia K562 cells via ROS toxicity
► DHA induced K562 cells autophagy followed by LC3-II protein expression. ► The DHA-induced autophagy might be ROS dependent. ► Inhibition of K562 cell proliferation by DHA was also dependent upon iron decrease.
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642128/ |