Relationship Between Bacterial Strain Type, Host Biomarkers, and Mortality in Clostridium difficile Infection

Relationship Between Bacterial Strain Type, Host Biomarkers, and Mortality in Clostridium difficile Infection

Clostridium difficile genotype predicts 14-day mortality in 1893 enzyme immunoassay–positive/culture-positive adults. Excess mortality correlates with genotype-specific changes in biomarkers, strongly implicating inflammatory pathways as a major influence on poor outcome. Polymerase chain reaction r...

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Bibliographic Details
Main Authors: Walker, A. Sarah, Eyre, David W., Wyllie, David H., Dingle, Kate E., Griffiths, David, Shine, Brian, Oakley, Sarah, O'Connor, Lily, Finney, John, Vaughan, Alison, Crook, Derrick W., Wilcox, Mark H., Peto, Tim E. A.
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641870/

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