Detection of Mixed Infection from Bacterial Whole Genome Sequence Data Allows Assessment of Its Role in Clostridium difficile Transmission

Bacterial whole genome sequencing offers the prospect of rapid and high precision investigation of infectious disease outbreaks. Close genetic relationships between microorganisms isolated from different infected cases suggest transmission is a strong possibility, whereas transmission between cases...

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Bibliographic Details
Main Authors: Eyre, David W., Cule, Madeleine L., Griffiths, David, Crook, Derrick W., Peto, Tim E. A., Walker, A. Sarah, Wilson, Daniel J.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642043/