Factor H Binds to the Hypervariable Region of Many Streptococcus pyogenes M Proteins but Does Not Promote Phagocytosis Resistance or Acute Virulence

Factor H Binds to the Hypervariable Region of Many Streptococcus pyogenes M Proteins but Does Not Promote Phagocytosis Resistance or Acute Virulence

Many pathogens express a surface protein that binds the human complement regulator factor H (FH), as first described for Streptococcus pyogenes and the antiphagocytic M6 protein. It is commonly assumed that FH recruited to an M protein enhances virulence by protecting the bacteria against complement...

Full description

Bibliographic Details
Main Authors: Gustafsson, Mattias C. U., Lannergård, Jonas, Nilsson, O. Rickard, Kristensen, Bodil M., Olsen, John E., Harris, Claire L., Ufret-Vincenty, Rafael L., Stålhammar-Carlemalm, Margaretha, Lindahl, Gunnar
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630203/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630203/

Similar Items