Inhibition of complement-mediated opsonization and phagocytosis of Streptococcus pyogenes by D fragments of fibrinogen and fibrin bound to cell surface M protein

The biological effects of the binding of fibrin(ogen) degradation products to M protein-bearing group A streptococci were investigated. Type 24 group A streptococci bind fibrinogen degradation products of the D family, but not fragment E. Binding appears to be mediated by M protein, since a large pe...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1985
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187975/