Loss of CclA, required for histone 3 lysine 4 methylation, decreases growth but increases secondary metabolite production in Aspergillus fumigatus

Loss of CclA, required for histone 3 lysine 4 methylation, decreases growth but increases secondary metabolite production in Aspergillus fumigatus

Secondary metabolite (SM) production in filamentous fungi is mechanistically associated with chromatin remodeling of specific SM clusters. One locus recently shown to be involved in SM suppression in Aspergillus nidulans was CclA, a member of the histone 3 lysine 4 methylating COMPASS complex. Here...

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Bibliographic Details
Main Authors: Palmer, Jonathan M., Bok, Jin Woo, Lee, Seul, Dagenais, Taylor R.T., Andes, David R., Kontoyiannis, Dimitrios P., Keller, Nancy P.
Format: Online
Language:English
Published: PeerJ Inc. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629006/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629006/

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