Transcriptional Regulation of Chemical Diversity in Aspergillus fumigatus by LaeA

Secondary metabolites, including toxins and melanins, have been implicated as virulence attributes in invasive aspergillosis. Although not definitively proved, this supposition is supported by the decreased virulence of an Aspergillus fumigatus strain, ΔlaeA, that is crippled in the production of nu...

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Bibliographic Details
Main Authors: Perrin, Robyn M, Fedorova, Natalie D, Bok, Jin Woo, Cramer, Robert A, Wortman, Jennifer R, Kim, H. Stanley, Nierman, William C, Keller, Nancy P
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851976/