Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas

Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas

Seminoma is a subclass of human testicular germ cell tumors (TGCT), the most frequently observed cancer in young men with a rising incidence. Here we describe the identification of a novel gene predisposing specifically to seminoma formation in a vertebrate model organism. Zebrafish carrying a heter...

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Bibliographic Details
Main Authors: Basten, Sander G., Davis, Erica E., Gillis, Ad J. M., van Rooijen, Ellen, Stoop, Hans, Babala, Nikolina, Logister, Ive, Heath, Zachary G., Jonges, Trudy N., Katsanis, Nicholas, Voest, Emile E., van Eeden, Freek J., Medema, Rene H., Ketting, René F., Schulte-Merker, Stefan, Looijenga, Leendert H. J., Giles, Rachel H.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627517/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627517/

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