Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer

by Medema, René H., Macurek, Libor
Published 2011

Localized Aurora B activity spatially controls non-kinetochore microtubules during spindle assembly

by Tanenbaum, Marvin E., Medema, René H.
Published 2011

Novel functions of FoxM1: from molecular mechanisms to cancer therapy

by Alvarez-Fernández, Mónica, Medema, René H.
Published 2013

Targeting the Mitotic Checkpoint to Kill Tumor Cells

by Janssen, Aniek, Kops, Geert J., Medema, René H.
Published 2010

The chromosomal passenger complex: guiding Aurora-B through mitosis

by Vader, Gerben, Medema, René H., Lens, Susanne M.A.
Published 2006

Systematic dissection of dynein regulators in mitosis

by Raaijmakers, Jonne A., Tanenbaum, Marvin E., Medema, René H.
Published 2013

Nuclear envelope-associated dynein cooperates with Eg5 to drive prophase centrosome separation

by van Heesbeen, Roy G.H.P., Raaijmakers, Jonne A., Tanenbaum, Marvin E., Medema, René H.
Published 2013

Spatial Separation of Plk1 Phosphorylation and Activity

by Bruinsma, Wytse, Aprelia, Melinda, Kool, Jolanda, Macurek, Libor, Lindqvist, Arne, Medema, René H.
Published 2015

Activation of Nuclear Factor-kappa B signalling promotes cellular senescence

by Rovillain, Emilie, Mansfield, Louise, Caetano, Catia, Alvarez-Fernandez, Monica, Caballero, Otavia L., Medema, Rene H., Hummerich, Holger, Jat, Parmjit S.
Published 2011

Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis

by Saurin, Adrian T., van der Waal, Maike S., Medema, René H., Lens, Susanne M.A., Kops, Geert J.P.L.
Published 2011

Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning

by Tame, Mihoko A, Raaijmakers, Jonne A, van den Broek, Bram, Lindqvist, Arne, Jalink, Kees, Medema, René H
Published 2014

Hypersensitivity to DNA damage in antephase as a safeguard for genome stability

by Feringa, Femke M., Krenning, Lenno, Koch, André, van den Berg, Jeroen, van den Broek, Bram, Jalink, Kees, Medema, René H.
Published 2016

Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease

by Domínguez-Kelly, Raquel, Martín, Yusé, Koundrioukoff, Stephane, Tanenbaum, Marvin E., Smits, Veronique A.J., Medema, René H., Debatisse, Michelle, Freire, Raimundo
Published 2011

Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint

by Kleiblova, Petra, Shaltiel, Indra A., Benada, Jan, Ševčík, Jan, Pecháčková, Soňa, Pohlreich, Petr, Voest, Emile E., Dundr, Pavel, Bartek, Jiri, Kleibl, Zdenek, Medema, René H., Macurek, Libor
Published 2013

Genome-wide RNAi screen for synthetic lethal interactions with the C. elegans kinesin-5 homolog BMK-1

by Maia, André F., Tanenbaum, Marvin E., Galli, Matilde, Lelieveld, Daphne, Egan, David A., Gassmann, Reto, Sunkel, Claudio E., van den Heuvel, Sander, Medema, René H.
Published 2015

The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment

by Monteiro, Lara J., Khongkow, Pasarat, Kongsema, Mesayamas, Morris, Joanna R., Man, Cornelia, Weekes, Daniel, Koo, Chuay-Yeng, Gomes, Ana R., Pinto, Paola H., Varghese, Vidhya, Kenny, Laura M., Coombes, R. Charles, Freire, Raimundo, Medema, René H., Lam, Eric W.-F.
Published 2012

Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening

by Elbatsh, Ahmed M.O., Haarhuis, Judith H.I., Petela, Naomi, Chapard, Christophe, Fish, Alexander, Celie, Patrick H., Stadnik, Magda, Ristic, Dejan, Wyman, Claire, Medema, René H., Nasmyth, Kim, Rowland, Benjamin D.
Published 2016

The core spliceosome as target and effector of non-canonical ATM signaling

by Tresini, Maria, Warmerdam, Daniël O., Kolovos, Petros, Snijder, Loes, Vrouwe, Mischa G., Demmers, Jeroen A.A., van IJcken, Wilfred F.J., Grosveld, Frank G., Medema, René H., Hoeijmakers, Jan H.J., Mullenders, Leon H.F., Vermeulen, Wim, Marteijn, Jurgen A.
Published 2015

Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas

by Basten, Sander G., Davis, Erica E., Gillis, Ad J. M., van Rooijen, Ellen, Stoop, Hans, Babala, Nikolina, Logister, Ive, Heath, Zachary G., Jonges, Trudy N., Katsanis, Nicholas, Voest, Emile E., van Eeden, Freek J., Medema, Rene H., Ketting, René F., Schulte-Merker, Stefan, Looijenga, Leendert H. J., Giles, Rachel H.
Published 2013

FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance

by Khongkow, Pasarat, Karunarathna, Upekha, Khongkow, Mattaka, Gong, Chun, Gomes, Ana R., Yagüe, Ernesto, Monteiro, Lara J., Kongsema, Mesayamas, Zona, Stefania, Man, Ellen P. S., Tsang, Janice W.-H., Coombes, R. Charles, Wu, Kou-Juey, Khoo, Ui-Soon, Medema, René H., Freire, Raimundo, Lam, Eric W.-F.
Published 2013