Human single-stranded DNA binding proteins are essential for maintaining genomic stability

The double-stranded conformation of cellular DNA is a central aspect of DNA stabilisation and protection. The helix preserves the genetic code against chemical and enzymatic degradation, metabolic activation, and formation of secondary structures. However, there are various instances where single-st...

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Bibliographic Details
Main Authors: Ashton, Nicholas W, Bolderson, Emma, Cubeddu, Liza, O’Byrne, Kenneth J, Richard, Derek J
Format: Online
Language:English
Published: BioMed Central 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626794/