Contribution of DEAF1 Structural Domains to the Interaction with the Breast Cancer Oncogene LMO4

by Cubeddu, Liza, Joseph, Soumya, Richard, Derek J., Matthews, Jacqueline M.
Published 2012

Human single-stranded DNA binding proteins are essential for maintaining genomic stability

by Ashton, Nicholas W, Bolderson, Emma, Cubeddu, Liza, O’Byrne, Kenneth J, Richard, Derek J
Published 2013

The Structure of an LIM-Only Protein 4 (LMO4) and Deformed Epidermal Autoregulatory Factor-1 (DEAF1) Complex Reveals a Common Mode of Binding to LMO4

by Joseph, Soumya, Kwan, Ann H., Stokes, Philippa H., Mackay, Joel P., Cubeddu, Liza, Matthews, Jacqueline M.
Published 2014

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity

by Richard, Derek J., Cubeddu, Liza, Urquhart, Aaron J., Bain, Amanda, Bolderson, Emma, Menon, Dinoop, White, Malcolm F., Khanna, Kum Kum
Published 2011

Sequence specificity of single-stranded DNA-binding proteins: a novel DNA microarray approach

by Morgan, Hugh P., Estibeiro, Peter, Wear, Martin A., Max, Klaas E.A., Heinemann, Udo, Cubeddu, Liza, Gallagher, Maurice P., Sadler, Peter J., Walkinshaw, Malcolm D.
Published 2007

hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex

by Richard, Derek J., Savage, Kienan, Bolderson, Emma, Cubeddu, Liza, So, Sairei, Ghita, Mihaela, Chen, David J., White, Malcolm F., Richard, Kerry, Prise, Kevin M., Schettino, Giuseppe, Khanna, Kum Kum
Published 2011

A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution

by Touma, Christine, Kariawasam, Ruvini, Gimenez, Adrian X., Bernardo, Ray E., Ashton, Nicholas W., Adams, Mark N., Paquet, Nicolas, Croll, Tristan I., O'Byrne, Kenneth J., Richard, Derek J., Cubeddu, Liza, Gamsjaeger, Roland
Published 2016

hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress

by Paquet, Nicolas, Adams, Mark N., Ashton, Nicholas W., Touma, Christine, Gamsjaeger, Roland, Cubeddu, Liza, Leong, Vincent, Beard, Sam, Bolderson, Emma, Botting, Catherine H., O’Byrne, Kenneth J., Richard, Derek J.
Published 2016

hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway

by Paquet, Nicolas, Adams, Mark N., Leong, Vincent, Ashton, Nicholas W., Touma, Christine, Gamsjaeger, Roland, Cubeddu, Liza, Beard, Sam, Burgess, Joshua T., Bolderson, Emma, O'Byrne, Ken J., Richard, Derek J.
Published 2015