Sulfhydration mediates neuroprotective actions of parkin

Sulfhydration mediates neuroprotective actions of parkin

Increases in S-nitrosylation and inactivation of the neuroprotective ubiquitin E3 ligase, parkin, in the brains of patients with Parkinson’s Disease (PD) are thought to be pathogenic and suggest a possible mechanism linking parkin to sporadic PD. Here we demonstrate that physiologic modification of...

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Bibliographic Details
Main Authors: Vandiver, M. Scott, Paul, Bindu D., Xu, Risheng, Karuppagounder, Senthilkumar, Rao, Feng, Snowman, Adele M., Ko, Han Seok, Lee, Yun Il, Dawson, Valina L., Dawson, Ted M., Sen, Nilkantha, Snyder, Solomon H.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622945/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622945/

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