Fastbreak: a tool for analysis and visualization of structural variations in genomic data

Genomic studies are now being undertaken on thousands of samples requiring new computational tools that can rapidly analyze data to identify clinically important features. Inferring structural variations in cancer genomes from mate-paired reads is a combinatorially difficult problem. We introduce Fa...

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Main Authors: Bressler, Ryan, Lin, Jake, Eakin, Andrea, Robinson, Thomas, Kreisberg, Richard, Rovira, Hector, Knijnenburg, Theo, Boyle, John, Shmulevich, Ilya
Format: Online
Language:English
Published: BioMed Central 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605143/
id pubmed-3605143
recordtype oai_dc
spelling pubmed-36051432013-03-22 Fastbreak: a tool for analysis and visualization of structural variations in genomic data Bressler, Ryan Lin, Jake Eakin, Andrea Robinson, Thomas Kreisberg, Richard Rovira, Hector Knijnenburg, Theo Boyle, John Shmulevich, Ilya Research Genomic studies are now being undertaken on thousands of samples requiring new computational tools that can rapidly analyze data to identify clinically important features. Inferring structural variations in cancer genomes from mate-paired reads is a combinatorially difficult problem. We introduce Fastbreak, a fast and scalable toolkit that enables the analysis and visualization of large amounts of data from projects such as The Cancer Genome Atlas. BioMed Central 2012 2012-10-09 /pmc/articles/PMC3605143/ /pubmed/23046488 http://dx.doi.org/10.1186/1687-4153-2012-15 Text en Copyright ©2012 Bressler et al; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Bressler, Ryan
Lin, Jake
Eakin, Andrea
Robinson, Thomas
Kreisberg, Richard
Rovira, Hector
Knijnenburg, Theo
Boyle, John
Shmulevich, Ilya
spellingShingle Bressler, Ryan
Lin, Jake
Eakin, Andrea
Robinson, Thomas
Kreisberg, Richard
Rovira, Hector
Knijnenburg, Theo
Boyle, John
Shmulevich, Ilya
Fastbreak: a tool for analysis and visualization of structural variations in genomic data
author_facet Bressler, Ryan
Lin, Jake
Eakin, Andrea
Robinson, Thomas
Kreisberg, Richard
Rovira, Hector
Knijnenburg, Theo
Boyle, John
Shmulevich, Ilya
author_sort Bressler, Ryan
title Fastbreak: a tool for analysis and visualization of structural variations in genomic data
title_short Fastbreak: a tool for analysis and visualization of structural variations in genomic data
title_full Fastbreak: a tool for analysis and visualization of structural variations in genomic data
title_fullStr Fastbreak: a tool for analysis and visualization of structural variations in genomic data
title_full_unstemmed Fastbreak: a tool for analysis and visualization of structural variations in genomic data
title_sort fastbreak: a tool for analysis and visualization of structural variations in genomic data
description Genomic studies are now being undertaken on thousands of samples requiring new computational tools that can rapidly analyze data to identify clinically important features. Inferring structural variations in cancer genomes from mate-paired reads is a combinatorially difficult problem. We introduce Fastbreak, a fast and scalable toolkit that enables the analysis and visualization of large amounts of data from projects such as The Cancer Genome Atlas.
publisher BioMed Central
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605143/
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