Soluble Guanylate Cyclase α1–Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma

Soluble Guanylate Cyclase α1–Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma

Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide. The molecular signaling involved in the pathogenesis of POAG remains unknown. Here, we report that mice lacking the α1 subunit of the nitric oxide receptor soluble guanylate cyclase represent a novel and translatable anima...

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Bibliographic Details
Main Authors: Buys, Emmanuel S., Ko, Yu-Chieh, Alt, Clemens, Hayton, Sarah R., Jones, Alexander, Tainsh, Laurel T., Ren, Ruiyi, Giani, Andrea, Clerté, Maeva, Abernathy, Emma, Tainsh, Robert E. T., Oh, Dong-Jin, Malhotra, Rajeev, Arora, Pankaj, de Waard, Nadine, Yu, Binglan, Turcotte, Raphael, Nathan, Daniel, Scherrer-Crosbie, Marielle, Loomis, Stephanie J., Kang, Jae H., Lin, Charles P., Gong, Haiyan, Rhee, Douglas J., Brouckaert, Peter, Wiggs, Janey L., Gregory, Meredith S., Pasquale, Louis R., Bloch, Kenneth D., Ksander, Bruce R.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603933/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603933/

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