Vasoreactivity to inhaled nitric oxide with oxygen predicts long-term survival in pulmonary arterial hypertension

by Malhotra, Rajeev, Hess, Dean, Lewis, Gregory D., Bloch, Kenneth D., Waxman, Aaron B., Semigran, Marc J.
Published 2011

Phosphomimetic Modulation of eNOS Improves Myocardial Reperfusion and Mimics Cardiac Postconditioning in Mice

by Pong, Terrence, Scherrer-Crosbie, Marielle, Atochin, Dmitriy N., Bloch, Kenneth D., Huang, Paul L.
Published 2014

Genetic mapping of a modifier locus affecting hypertension in soluble guanylate cyclase α1 deficient mice

by Buys, Emmanuel S, Raher, Michael J, Kirby, Andrew, Hayton, Sarah R, Tainsh, Laurel T, Sips, Patrick Y, Brouckaert, Peter, Daly, Mark J, Bloch, Kenneth D
Published 2011

Deletion of the Murine Cytochrome P450 Cyp2j Locus by Fused BAC-Mediated Recombination Identifies a Role for Cyp2j in the Pulmonary Vascular Response to Hypoxia

by Zhou, Guo Ling, Beloiartsev, Arkadi, Yu, Binglan, Baron, David M., Zhou, Weihua, Niedra, Rasma, Lu, Naifang, Tainsh, Laurel T., Zapol, Warren M., Seed, Brian, Bloch, Kenneth D.
Published 2013

Deletion of the Sequence Encoding the Tail Domain of the Bone Morphogenetic Protein type 2 Receptor Reveals a Bone Morphogenetic Protein 7-Specific Gain of Function

by Leyton, Patricio A., Beppu, Hideyuki, Pappas, Alexandra, Martyn, Trejeeve M., Derwall, Matthias, Baron, David M., Galdos, Rita, Bloch, Donald B., Bloch, Kenneth D.
Published 2013

sGCα1-deficient mice: a novel murine model of spontaneous primary open angle glaucoma

by Buys, Emmanuel S, Ko, Yu-Chieh, Hayton, Sarah, Jones, Alexander, Tainsh, Laurel, Ren, Ruiyi, Giani, Andrea, Abernathy, Emma, Gong, Haiyan, Rhee, Douglas J, Brouckaert, Peter, Gregory, Meredith, Pasquale, Louis R, Bloch, Kenneth D, Ksander, Bruce
Published 2011

sGCα1β1 attenuates cardiac dysfunction and mortality in murine inflammatory shock models

by Buys, Emmanuel S, Cauwels, Anje, Raher, Michael J, Passeri, Jonathan J, Hobai, Ion, Cawley, Sharon M, Rauwerdink, Kristen M, Thibault, Helene, Sips, Patrick Y, Thoonen, Robrecht, Scherrer-Crosbie, Marielle, Ichinose, Fumito, Brouckaert, Peter, Bloch, Kenneth D
Published 2009

MicroRNA miR-425 is a negative regulator of atrial natriuretic peptide

by Arora, Pankaj, Wu, Connie, Bloch, Donald B, Davis-Dusenbury, Brandi N, Spagnolli, Ester, Hata, Akiko, Vandenwijngaert, Sara, Swinnen, Melissa, Janssens, Stefan, Buys, Emmanuel S, Bloch, Kenneth D, Newton-Cheh, Christopher, Wang, Thomas J
Published 2013

Cardiac soluble guanylate cyclase protects against the cardiac dysfunction induced by chronic doxorubicin treatment in mice

by Vandenwijngaert, Sara, Swinnen, Melissa, Gillijns, Hilde, Caluwé, Ellen, Tainsh, Robert E, Nathan, Daniel I, Allen, Kaitlin, Bartunek, Jozef, Brouckaert, Peter, Scherrer-Crosbie, Marielle, Bloch, Kenneth D, Janssens, Stefan P, Buys, Emmanuel S
Published 2015

Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling

by Nakagawa, Akito, Lui, Francine E., Wassaf, Dina, Yefidoff-Freedman, Revital, Casalena, Dominick, Palmer, Michelle A., Meadows, Jacqueline, Mozzarelli, Andrea, Ronda, Luca, Abdulmalik, Osheiza, Bloch, Kenneth D., Safo, Martin K., Zapol, Warren M.
Published 2014

Increased Cardiac Myocyte PDE5 Levels in Human and Murine Pressure Overload Hypertrophy Contribute to Adverse LV Remodeling

by Vandenwijngaert, Sara, Pokreisz, Peter, Hermans, Hadewich, Gillijns, Hilde, Pellens, Marijke, Bax, Noortje A. M., Coppiello, Giulia, Oosterlinck, Wouter, Balogh, Agnes, Papp, Zoltan, Bouten, Carlijn V. C., Bartunek, Jozef, D'hooge, Jan, Luttun, Aernout, Verbeken, Erik, Herregods, Marie Christine, Herijgers, Paul, Bloch, Kenneth D., Janssens, Stefan
Published 2013

Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial

by Mwanga-Amumpaire, Juliet, Carroll, Ryan W., Baudin, Elisabeth, Kemigisha, Elisabeth, Nampijja, Dorah, Mworozi, Kenneth, Santorino, Data, Nyehangane, Dan, Nathan, Daniel I., De Beaudrap, Pierre, Etard, Jean-François, Feelisch, Martin, Fernandez, Bernadette O., Berssenbrugge, Annie, Bangsberg, David, Bloch, Kenneth D., Boum, Yap, Zapol, Warren M.
Published 2015

Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice

by Thoonen, Robrecht, Cauwels, Anje, Decaluwe, Kelly, Geschka, Sandra, Tainsh, Robert E., Delanghe, Joris, Hochepied, Tino, De Cauwer, Lode, Rogge, Elke, Voet, Sofie, Sips, Patrick, Karas, Richard H., Bloch, Kenneth D., Vuylsteke, Marnik, Stasch, Johannes-Peter, Van de Voorde, Johan, Buys, Emmanuel S., Brouckaert, Peter
Published 2015

Androgen-sensitive hypertension associated with soluble guanylate cyclase alpha1 deficiency is mediated by 20-HETE

by Vandenwijngaert, Sara, Dordea, Ana C, Garcia, Victor, Tainsh, Robert E, Nathan, Daniel I, Raher, Michael J, Allen, Kaitlin, Zhang, Fan, Lieb, Wolfgang S, Mikelman, Sarah, Kirby, Andrew, Stevens, Christine, Thoonen, Robrecht, Hindle, Allyson, Sips, Patrick Y, Malhotra, Rajeev, Daly, Mark J, Brouckaert, Peter, Bloch, Kenneth D, Schwartzman, Michal, Buys, Emmanuel S
Published 2015

Weight Loss, Saline Loading, and the Natriuretic Peptide System

by Arora, Pankaj, Reingold, Jason, Baggish, Aaron, Guanaga, Derek P., Wu, Connie, Ghorbani, Anahita, Song, Yanna, Chen‐Tournaux, Annabel, Khan, Abigail May, Tainsh, Laurel T., Buys, Emmanuel S., Williams, Jonathan S., Heublein, Denise M., Burnett, John C., Semigran, Marc J., Bloch, Kenneth D., Scherrer‐Crosbie, Marielle, Newton‐Cheh, Christopher, Kaplan, Lee M., Wang, Thomas J.
Published 2015

Inhibition of Bone Morphogenetic Protein Signal Transduction Prevents the Medial Vascular Calcification Associated with Matrix Gla Protein Deficiency

by Malhotra, Rajeev, Burke, Megan F., Martyn, Trejeeve, Shakartzi, Hannah R., Thayer, Timothy E., O’Rourke, Caitlin, Li, Pingcheng, Derwall, Matthias, Spagnolli, Ester, Kolodziej, Starsha A., Hoeft, Konrad, Mayeur, Claire, Jiramongkolchai, Pawina, Kumar, Ravindra, Buys, Emmanuel S., Yu, Paul B., Bloch, Kenneth D., Bloch, Donald B.
Published 2015

Soluble Guanylate Cyclase α1–Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma

by Buys, Emmanuel S., Ko, Yu-Chieh, Alt, Clemens, Hayton, Sarah R., Jones, Alexander, Tainsh, Laurel T., Ren, Ruiyi, Giani, Andrea, Clerté, Maeva, Abernathy, Emma, Tainsh, Robert E. T., Oh, Dong-Jin, Malhotra, Rajeev, Arora, Pankaj, de Waard, Nadine, Yu, Binglan, Turcotte, Raphael, Nathan, Daniel, Scherrer-Crosbie, Marielle, Loomis, Stephanie J., Kang, Jae H., Lin, Charles P., Gong, Haiyan, Rhee, Douglas J., Brouckaert, Peter, Wiggs, Janey L., Gregory, Meredith S., Pasquale, Louis R., Bloch, Kenneth D., Ksander, Bruce R.
Published 2013