Targeting SIRPα in cancer
Strategies to harness the patient’s immune system to fight cancer have mainly involved adoptive T-cell transfer. We and others have recently highlighted an alternative immunotherapeutic approach to cancer that consists of enhancing the macrophage-mediated clearance of leukemia cells through the bloc...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Landes Bioscience
2013
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601179/ |
| id |
pubmed-3601179 |
|---|---|
| recordtype |
oai_dc |
| spelling |
pubmed-36011792013-03-22 Targeting SIRPα in cancer Ho, Jenny M. Danska, Jayne S. Wang, Jean C.Y. Author's View Strategies to harness the patient’s immune system to fight cancer have mainly involved adoptive T-cell transfer. We and others have recently highlighted an alternative immunotherapeutic approach to cancer that consists of enhancing the macrophage-mediated clearance of leukemia cells through the blockade of inhibitory signals transmitted by signal regulatory protein α (SIRPα). Landes Bioscience 2013-02-01 /pmc/articles/PMC3601179/ /pubmed/23525504 http://dx.doi.org/10.4161/onci.23081 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Ho, Jenny M. Danska, Jayne S. Wang, Jean C.Y. |
| spellingShingle |
Ho, Jenny M. Danska, Jayne S. Wang, Jean C.Y. Targeting SIRPα in cancer |
| author_facet |
Ho, Jenny M. Danska, Jayne S. Wang, Jean C.Y. |
| author_sort |
Ho, Jenny M. |
| title |
Targeting SIRPα in cancer |
| title_short |
Targeting SIRPα in cancer |
| title_full |
Targeting SIRPα in cancer |
| title_fullStr |
Targeting SIRPα in cancer |
| title_full_unstemmed |
Targeting SIRPα in cancer |
| title_sort |
targeting sirpα in cancer |
| description |
Strategies to harness the patient’s immune system to fight cancer have mainly involved adoptive T-cell transfer. We and others have recently highlighted an alternative immunotherapeutic approach to cancer that consists of enhancing the macrophage-mediated clearance of leukemia cells through the blockade of inhibitory signals transmitted by signal regulatory protein α (SIRPα). |
| publisher |
Landes Bioscience |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601179/ |
| _version_ |
1611963545442844672 |