Targeting SIRPα in cancer

Strategies to harness the patient’s immune system to fight cancer have mainly involved adoptive T-cell transfer. We and others have recently highlighted an alternative immunotherapeutic approach to cancer that consists of enhancing the macrophage-mediated clearance of leukemia cells through the bloc...

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Bibliographic Details
Main Authors: Ho, Jenny M., Danska, Jayne S., Wang, Jean C.Y.
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601179/