The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes
IL-6 is a pleiotropic cytokine involved in the regulation of the immune response, inflammation, and hematopoeisis. Its elevated levels are found in a range of autoimmune and chronic inflammatory diseases. IL-6 is also involved in regulation of the balance between two T cell subsets: Tregs and Th17,...
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| Format: | Online |
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Hindawi Publishing Corporation
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595664/ |
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pubmed-3595664 |
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pubmed-35956642013-03-26 The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes Ryba-Stanisławowska, Monika Skrzypkowska, Maria Myśliwska, Jolanta Myśliwiec, Małgorzata Research Article IL-6 is a pleiotropic cytokine involved in the regulation of the immune response, inflammation, and hematopoeisis. Its elevated levels are found in a range of autoimmune and chronic inflammatory diseases. IL-6 is also involved in regulation of the balance between two T cell subsets: Tregs and Th17, which have contradictory functions in the control of inflammation. The present study provides a quantitative analysis regarding the Th17/Treg cell balance in peripheral blood of children with type 1 diabetes and its association with serum IL-6 level. Hindawi Publishing Corporation 2013 2013-02-21 /pmc/articles/PMC3595664/ /pubmed/23533301 http://dx.doi.org/10.1155/2013/205284 Text en Copyright © 2013 Monika Ryba-Stanisławowska et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Ryba-Stanisławowska, Monika Skrzypkowska, Maria Myśliwska, Jolanta Myśliwiec, Małgorzata |
| spellingShingle |
Ryba-Stanisławowska, Monika Skrzypkowska, Maria Myśliwska, Jolanta Myśliwiec, Małgorzata The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes |
| author_facet |
Ryba-Stanisławowska, Monika Skrzypkowska, Maria Myśliwska, Jolanta Myśliwiec, Małgorzata |
| author_sort |
Ryba-Stanisławowska, Monika |
| title |
The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes |
| title_short |
The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes |
| title_full |
The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes |
| title_fullStr |
The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes |
| title_full_unstemmed |
The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes |
| title_sort |
serum il-6 profile and treg/th17 peripheral cell populations in patients with type 1 diabetes |
| description |
IL-6 is a pleiotropic cytokine involved in the regulation of the immune response, inflammation, and hematopoeisis. Its elevated levels are found in a range of autoimmune and chronic inflammatory diseases. IL-6 is also involved in regulation of the balance between two T cell subsets: Tregs and Th17, which have contradictory functions in the control of inflammation. The present study provides a quantitative analysis regarding the Th17/Treg cell balance in peripheral blood of children with type 1 diabetes and its association with serum IL-6 level. |
| publisher |
Hindawi Publishing Corporation |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595664/ |
| _version_ |
1611961601436418048 |