Elevated Levels of Serum IL-12 and IL-18 are Associated with Lower Frequencies of CD4+CD25highFOXP3+ Regulatory T cells in Young Patients with Type 1 Diabetes
Type 1 diabetes is thought to involve chronic inflammation, which is manifested by the activation and expression of different inflammatory mediators. IL-12 and IL-18 are two cytokines that have been shown to exert strong proinflammatory activity and have been implicated in the pathogenesis of type 1...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer US
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174326/ |