Interpretation of Genomic Variants Using a Unified Biological Network Approach
The decreasing cost of sequencing is leading to a growing repertoire of personal genomes. However, we are lagging behind in understanding the functional consequences of the millions of variants obtained from sequencing. Global system-wide effects of variants in coding genes are particularly poorly u...
Main Authors: | Khurana, Ekta, Fu, Yao, Chen, Jieming, Gerstein, Mark |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591262/ |
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