A new shrinkage estimator for dispersion improves differential expression detection in RNA-seq data
Recent developments in RNA-sequencing (RNA-seq) technology have led to a rapid increase in gene expression data in the form of counts. RNA-seq can be used for a variety of applications, however, identifying differential expression (DE) remains a key task in functional genomics. There have been a num...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Oxford University Press
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590927/ |