Error estimates for the analysis of differential expression from RNA-seq count data
Background. A number of algorithms exist for analysing RNA-sequencing data to infer profiles of differential gene expression. Problems inherent in building algorithms around statistical models of over dispersed count data are formidable and frequently lead to non-uniform p-value distributions for nu...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
PeerJ Inc.
2014
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179614/ |