Bioluminescence Imaging Reveals Dynamics of Beta Cell Loss in the Non-Obese Diabetic (NOD) Mouse Model

Bioluminescence Imaging Reveals Dynamics of Beta Cell Loss in the Non-Obese Diabetic (NOD) Mouse Model

We generated a mouse model (MIP-Luc-VU-NOD) that enables non-invasive bioluminescence imaging (BLI) of beta cell loss during the progression of autoimmune diabetes and determined the relationship between BLI and disease progression. MIP-Luc-VU-NOD mice displayed insulitis and a decline in biolumines...

Full description

Bibliographic Details
Main Authors:	Virostko, John, Radhika, Armandla, Poffenberger, Greg, Dula, Adrienne N., Moore, Daniel J., Powers, Alvin C.
Format:	Online
Language:	English
Published:	Public Library of Science 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590285/

Similar Items

Bioluminescence imaging reveals dynamics of beta cell loss in the non-obese diabetic (NOD) mouse model.
by: John Virostko, et al.

Non-Invasive Bioluminescence Imaging of β-Cell Function in Obese-Hyperglycemic [ob/ob] Mice
by: Patel, Manishkumar, et al.
Published: (2014)

Paquinimod prevents development of diabetes in the non-obese diabetic (NOD) mouse.
by: Sahar Tahvili, et al.

Bioluminescence
by: Shakeeb Arsalaan Bajunid, Siti Farhana Bajunid, et al.
Published: (2017)

Use of the Electronic Medical Record to Assess Pancreas Size in Type 1 Diabetes
by: Virostko, John, et al.
Published: (2016)

Fluorescent and Bioluminescent Reporter Myxoviruses
by: Rostad, Christina A., et al.
Published: (2016)

Fiat Luc: Bioluminescence Imaging Reveals In Vivo Viral Replication Dynamics
by: Mehle, Andrew
Published: (2015)

Characterization of an anthraquinone fluor from the bioluminescent, pelagic polychaete Tomopteris
by: Francis, Warren R, et al.
Published: (2014)

Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice
by: Reinert, Rachel B., et al.
Published: (2012)

Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice
by: Dou, Shuping, et al.
Published: (2014)

Prolonged Bioluminescence Monitoring in Mouse Ex Vivo Bone Culture Revealed Persistent Circadian Rhythms in Articular Cartilages and Growth Plates
by: Okubo, Naoki, et al.
Published: (2013)

In vivo Bioluminescence Imaging of Burkholderia mallei Respiratory Infection and Treatment in the Mouse Model
by: Massey, Shane, et al.
Published: (2011)

In vivo bioluminescence imaging for leptomeningeal dissemination of medulloblastoma in mouse models
by: Choi, Seung Ah, et al.
Published: (2016)

Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure
by: Giorgi, Carlotta, et al.
Published: (2011)

Analysis of Neurogenesis during Experimental Autoimmune Encephalomyelitis Reveals Pitfalls of Bioluminescence Imaging
by: Ayzenberg, Ilya, et al.
Published: (2015)

Occurrence of Isopenicillin-N-Synthase Homologs in Bioluminescent Ctenophores and Implications for Coelenterazine Biosynthesis
by: Francis, Warren R., et al.
Published: (2015)

Broad Spectrum Bioluminescence: Shine On!
by: Mixter, Phil
Published: (2013)

Combining fluorescence and bioluminescence microscopy
by: Goda, Kazuhito, et al.
Published: (2015)

Illuminating Fungal Infections with Bioluminescence
by: Papon, Nicolas, et al.
Published: (2014)

NOD1 and NOD2 Signaling in Infection and Inflammation
by: Moreira, Lilian O., et al.
Published: (2012)

Resveratrol improves salivary dysfunction in a non-obese diabetic (NOD) mouse model of Sjögren’s syndrome
by: Inoue, Hiroko, et al.
Published: (2016)

Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain
by: Salbaum, J. Michael, et al.
Published: (2015)

Bioluminescent Imaging and Histopathologic Characterization of WEEV Neuroinvasion in Outbred CD-1 Mice
by: Phillips, Aaron T., et al.
Published: (2013)

Longitudinal Bioluminescence Imaging of the Dynamics of Doxorubicin Induced Apoptosis
by: Niu, Gang, et al.
Published: (2013)

IL-2 Immunotherapy Reveals Potential for Innate Beta Cell Regeneration in the Non-Obese Diabetic Mouse Model of Autoimmune Diabetes
by: Diaz-de-Durana, Yaiza, et al.
Published: (2013)

Genetic Analysis of Substrain Divergence in Non-Obese Diabetic (NOD) Mice
by: Simecek, Petr, et al.
Published: (2015)

Nodding Syndrome
by: Dowell, Scott F., et al.
Published: (2013)

In vivo Dual Substrate Bioluminescent Imaging
by: Wendt, Michael K., et al.
Published: (2011)

KINETICS OF THE BIOLUMINESCENT REACTION IN CYPRIDINA. II
by: Amberson, William R.
Published: (1922)

STUDIES ON BIOLUMINESCENCE : XV. ELECTROREDUCTION OF OXYLUCIFERIN.
by: Harvey, E. Newton
Published: (1923)

KINETICS OF THE BIOLUMINESCENT REACTION IN CYPRIDINA. I
by: Amberson, William R.
Published: (1922)

The Subcellular Origin of Bioluminescence in Noctiluca miliaris
by: Eckert, Roger, et al.
Published: (1967)

Metabolic imaging in tumours by means of bioluminescence.
by: Tamulevicius, P., et al.
Published: (1995)

The Expanding Toolbox of In Vivo Bioluminescent Imaging
by: Xu, Tingting, et al.
Published: (2016)

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse
Published: (1987)

IFN Regulatory Factors 4 and 8 Expression in the NOD Mouse
by: Besin, Gilles, et al.
Published: (2011)

Gene Targeting in NOD Mouse Embryos Using Zinc-Finger Nucleases
by: Chen, Yi-Guang, et al.
Published: (2014)

Mouse Paneth cell antimicrobial function is independent of Nod2
by: Shanahan, Michael T, et al.
Published: (2014)

Defining the Transcriptional and Cellular Landscape of Type 1 Diabetes in the NOD Mouse
by: Carrero, Javier A., et al.
Published: (2013)

Correction: Defining the Transcriptional and Cellular Landscape of Type 1 Diabetes in the NOD Mouse
by: Carrero, Javier A., et al.
Published: (2014)