The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype
We previously demonstrated inhibition of ovalbumin-induced allergic airway hyper-responsiveness in the mouse using ES-62, a phosphorylcholine-containing glycoprotein secreted by the filarial nematode, Acanthocheilonema viteae. This inhibition correlated with ES-62-induced mast cell desensitisation,...
Main Authors: | , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Elsevier Science
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584281/ |