Cell type and context-specific function of PLAG1 for IGF2 P3 promoter activity
The fetal transcription factor PLAG1 is found to be overexpressed in cancers, and has been suggested to bind the insulin like growth factor 2 (IGF2) P3 promoter, and to activate the IGF2 gene. The expression of IGF2 has partly been linked to loss of CTCF-dependent chromatin insulator function at the...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
D.A. Spandidos
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583874/ |