Nuclear Receptor Corepressors are Required for the Histone Deacetylase Activity of HDAC3 In Vivo

Histone deacetylase 3 (HDAC3) is an epigenome-modifying enzyme that is required for normal mouse development and tissue-specific functions. In vitro, HDAC3 protein itself has minimal enzyme activity, but gains its histone deacetylation function from stable association with the conserved deacetylase...

Full description

Bibliographic Details
Main Authors: You, Seo-Hee, Lim, Hee-Woong, Sun, Zheng, Broache, Molly, Won, Kyoung-Jae, Lazar, Mitchell A.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565028/