Nuclear receptor corepressors and PPARγ

The nuclear receptor corepressors NCoR and SMRT repress gene transcription by recruiting a histone deacetylase complex. Their roles in PPARγ action have been controversial. Recent evidence, however, suggests that NCoR and SMRT repress PPARγ-mediated transcriptional activity on specific promoters i...

Full description

Bibliographic Details
Main Author: Cohen, Ronald N.
Format: Online
Language:English
Published: The Nuclear Receptor Signaling Atlas 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402213/