Nuclear receptor corepressors and PPARγ
The nuclear receptor corepressors NCoR and SMRT repress gene transcription by recruiting a histone deacetylase complex. Their roles in PPARγ action have been controversial. Recent evidence, however, suggests that NCoR and SMRT repress PPARγ-mediated transcriptional activity on specific promoters i...
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Format: | Online |
Language: | English |
Published: |
The Nuclear Receptor Signaling Atlas
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402213/ |