Latent Regulatory Potential of Human-Specific Repetitive Elements
At least half of the human genome is derived from repetitive elements, which are often lineage specific and silenced by a variety of genetic and epigenetic mechanisms. Using a transchromosomic mouse strain that transmits an almost complete single copy of human chromosome 21 via the female germline,...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Cell Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560060/ |